Treatment options by stage

Treatment options by stage
1 icon

Standard treatments to control the prostate cancer.

  • Active surveillance.
  • Radical prostatectomy, usually with pelvic lymphadenectomy.
  • External beam radiotherapy.
  • Brachytherapy – interstitial implants of radioactive seeds.
  • Clinical trials of new therapies may be an option.
2 icon

Standard treatments to control the prostate cancer.

  • Active surveillance.
  • Radical prostatectomy, usually with pelvic lymphadenectomy. Radiotherapy may also be given after surgery.
  • External beam radiotherapy. Hormone therapy may be recommended after the radiotherapy.
  • Brachytherapy.
  • Clinical trials with new therapies may be an option.
3 icon

Treatments usually include a combination of brachytherapy, radiotherapy, hormonal therapy and surgery to alleviate urinary symptoms. Patients at stage III are at high risk for metastatic spread of prostate cancer. The treatment goal is to maximally destroy the cancer and reduce the possibility of further spread. Some patients may have untraceable metastatic spread which requires indefinite systemic hormonal treatment.

  • External radiotherapy. Hormone therapy is consistently recommended with and after the radiotherapy.
  • Hormone therapy, usually in conjunction with other treatment method and may be continued indefinitely.
  • Radical prostatectomy is uncommon and performed only in selected patients and typically followed by external radiation and hormone therapy.
  • Brachytherapy and external radiotherapy routinely together with hormone therapy.
  • Transurethral resection of the prostate (TURP) to alleviate urinary symptoms.
  • Watchful waiting (observation).
  • Clinical trials with new therapies may be an option.
4 icon

The goals of treatment focus on slowing disease progression, improving quality of life and increasing survival time.

  • Hormone therapy.
  • Chemotherapy in combination with hormone therapy.
  • Palliative external radiotherapy to control symptoms or prevent fracture of affected by cancer bones.
  • Palliative internal radiotherapy.
  • Transurethral resection of the prostate (TURP).
  • Watchful waiting (observation).
  1. American Cancer Society. Initial Treatment of Prostate Cancer, by Stage and Risk Group. https://www.cancer.org/cancer/prostate-cancer/treating/by-stage.html. Accessed on 22 October 2021.

References

IFPA. Psoriasis is a serious disease deserving global attention. Available at: https://ifpa-pso.com/wp-content/uploads/2017/01/Brochure-Psoriasis-is-a-serious-disease-deserving-global-attention.pdf Accessed: June 2020.
Rapp SR, et al. J Am Acad Dermatol 1999;41:401–7.
NHS. Living with psoriasis. Available at: https://www.nhs.uk/conditions/psoriasis/living-with/ Accessed: June 2020.
Griffiths CEM and Barker JNWN. Lancet 2007;370:263-71.
Reich A, et al. Acta Derm Venereol 2010;90:257-63.
Heller MM, et al. Skin Ther Letter 2011;16.
Moon H-S, et al. Dermatol Ther 2013;3:117-30.
NHS. Clinical depression. Available at: https://www.nhs.uk/conditions/clinical-depression/symptoms/ Accessed: June 2020.
Pulse Today. Almost half of GP consultations ‘now include a mental health issue’. Available at: http://www.pulsetoday.co.uk/clinical/clinical-specialties/mental-health/almost-half-of-gp-consultations-now-include-a-mental-health-issue/20036839.article Accessed: June 2020.
NHS. CBT. Available at: https://www.nhs.uk/conditions/cognitive-behavioural-therapy-cbt/ Accessed: June 2020.
Markowitz JC and Weissman MM. World Psych 2004;3(3):136-9.
NHS. Counselling. Available at: https://www.nhs.uk/conditions/counselling/ Accessed: June 2020.